American Institute of Mathematical Sciences

2014, 11(5): 1199-1214. doi: 10.3934/mbe.2014.11.1199

Effect of residual stress on peak cap stress in arteries

 1 St. Olaf College, 1520 St. Olaf Ave, Northfield, MN 55057, United States

Received  January 2014 Revised  April 2014 Published  June 2014

Vulnerable plaques are a subset of atherosclerotic plaques that are prone to rupture when high stresses occur in the cap. The roles of residual stress, plaque morphology, and cap stiffness on the cap stress are not completely understood. Here, arteries are modeled within the framework of nonlinear elasticity as incompressible cylindrical structures that are residually stressed through differential growth. These structures are assumed to have a nonlinear, anisotropic, hyperelastic response to stresses in the media and adventitia layers and an isotropic response in the intima and necrotic layers. The effect of differential growth on the peak stress is explored in a simple, concentric geometry and it is shown that axial differential growth decreases the peak stress in the inner layer. Furthermore, morphological risk factors are explored. The peak stress in residually stressed cylinders is not greatly affected by changing the thickness of the intima. The thickness of the necrotic layer is shown to be the most important morphological feature that affects the peak stress in a residually stressed vessel.
Citation: Rebecca Vandiver. Effect of residual stress on peak cap stress in arteries. Mathematical Biosciences & Engineering, 2014, 11 (5) : 1199-1214. doi: 10.3934/mbe.2014.11.1199
References:

show all references

References:
 [1] Gunther Uhlmann, Jenn-Nan Wang. Unique continuation property for the elasticity with general residual stress. Inverse Problems & Imaging, 2009, 3 (2) : 309-317. doi: 10.3934/ipi.2009.3.309 [2] Victor Isakov, Nanhee Kim. Weak Carleman estimates with two large parameters for second order operators and applications to elasticity with residual stress. Discrete & Continuous Dynamical Systems - A, 2010, 27 (2) : 799-825. doi: 10.3934/dcds.2010.27.799 [3] Victor Isakov. Carleman estimates for some anisotropic elasticity systems and applications. Evolution Equations & Control Theory, 2012, 1 (1) : 141-154. doi: 10.3934/eect.2012.1.141 [4] Nanhee Kim. Uniqueness and Hölder type stability of continuation for the linear thermoelasticity system with residual stress. Evolution Equations & Control Theory, 2013, 2 (4) : 679-693. doi: 10.3934/eect.2013.2.679 [5] Annie Raoult. Symmetry groups in nonlinear elasticity: an exercise in vintage mathematics. Communications on Pure & Applied Analysis, 2009, 8 (1) : 435-456. doi: 10.3934/cpaa.2009.8.435 [6] Irena Lasiecka, W. Heyman. Asymptotic behavior of solutions in nonlinear dynamic elasticity. Discrete & Continuous Dynamical Systems - A, 1995, 1 (2) : 237-252. doi: 10.3934/dcds.1995.1.237 [7] Lorena Bociu, Jean-Paul Zolésio. Existence for the linearization of a steady state fluid/nonlinear elasticity interaction. Conference Publications, 2011, 2011 (Special) : 184-197. doi: 10.3934/proc.2011.2011.184 [8] Francois van Heerden, Zhi-Qiang Wang. On a class of anisotropic nonlinear elliptic equations in $\mathbb R^N$. Communications on Pure & Applied Analysis, 2008, 7 (1) : 149-162. doi: 10.3934/cpaa.2008.7.149 [9] Naoufel Ben Abdallah, Yongyong Cai, Francois Castella, Florian Méhats. Second order averaging for the nonlinear Schrödinger equation with strongly anisotropic potential. Kinetic & Related Models, 2011, 4 (4) : 831-856. doi: 10.3934/krm.2011.4.831 [10] Mostafa Bendahmane, Kenneth Hvistendahl Karlsen, Mazen Saad. Nonlinear anisotropic elliptic and parabolic equations with variable exponents and $L^1$ data. Communications on Pure & Applied Analysis, 2013, 12 (3) : 1201-1220. doi: 10.3934/cpaa.2013.12.1201 [11] Michael Kiermaier, Reinhard Laue. Derived and residual subspace designs. Advances in Mathematics of Communications, 2015, 9 (1) : 105-115. doi: 10.3934/amc.2015.9.105 [12] Irena PawŃow, Wojciech M. Zajączkowski. Global regular solutions to three-dimensional thermo-visco-elasticity with nonlinear temperature-dependent specific heat. Communications on Pure & Applied Analysis, 2017, 16 (4) : 1331-1372. doi: 10.3934/cpaa.2017065 [13] Julian Braun, Bernd Schmidt. On the passage from atomistic systems to nonlinear elasticity theory for general multi-body potentials with p-growth. Networks & Heterogeneous Media, 2013, 8 (4) : 879-912. doi: 10.3934/nhm.2013.8.879 [14] Shuai Zhang, L.R. Ritter, A.I. Ibragimov. Foam cell formation in atherosclerosis: HDL and macrophage reverse cholesterol transport. Conference Publications, 2013, 2013 (special) : 825-835. doi: 10.3934/proc.2013.2013.825 [15] Telma Silva, Adélia Sequeira, Rafael F. Santos, Jorge Tiago. Existence, uniqueness, stability and asymptotic behavior of solutions for a mathematical model of atherosclerosis. Discrete & Continuous Dynamical Systems - S, 2016, 9 (1) : 343-362. doi: 10.3934/dcdss.2016.9.343 [16] Donatella Donatelli, Corrado Lattanzio. On the diffusive stress relaxation for multidimensional viscoelasticity. Communications on Pure & Applied Analysis, 2009, 8 (2) : 645-654. doi: 10.3934/cpaa.2009.8.645 [17] Chiara Corsato, Colette De Coster, Franco Obersnel, Pierpaolo Omari, Alessandro Soranzo. A prescribed anisotropic mean curvature equation modeling the corneal shape: A paradigm of nonlinear analysis. Discrete & Continuous Dynamical Systems - S, 2018, 11 (2) : 213-256. doi: 10.3934/dcdss.2018013 [18] Jean-Claude Saut, Jun-Ichi Segata. Asymptotic behavior in time of solution to the nonlinear Schrödinger equation with higher order anisotropic dispersion. Discrete & Continuous Dynamical Systems - A, 2019, 39 (1) : 219-239. doi: 10.3934/dcds.2019009 [19] Silvia Frassu. Nonlinear Dirichlet problem for the nonlocal anisotropic operator $L_K$. Communications on Pure & Applied Analysis, 2019, 18 (4) : 1847-1867. doi: 10.3934/cpaa.2019086 [20] Tuan Hiep Pham, Jérôme Laverne, Jean-Jacques Marigo. Stress gradient effects on the nucleation and propagation of cohesive cracks. Discrete & Continuous Dynamical Systems - S, 2016, 9 (2) : 557-584. doi: 10.3934/dcdss.2016012

2018 Impact Factor: 1.313