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*uniqueness*of weak solutions. This result is proved for the same (even larger) class of data for which existence theory holds. In addition, we prove that weak solutions are continuously depending on initial data and that the flow corresponding to weak and global solutions is a dynamical system on the finite energy space.

The main goal of this work is to clarify and quantify, by means of mathematical analysis, the role of structural viscoelasticity in the biomechanical response of deformable porous media with incompressible constituents to sudden changes in external applied loads. Models of deformable porous media with incompressible constituents are often utilized to describe the behavior of biological tissues, such as cartilages, bones and engineered tissue scaffolds, where viscoelastic properties may change with age, disease or by design. Here, for the first time, we show that the fluid velocity within the medium could increase tremendously, even up to infinity, should the external applied load experience sudden changes in time and the structural viscoelasticity be too small. In particular, we consider a one-dimensional poro-visco-elastic model for which we derive explicit solutions in the cases where the external applied load is characterized by a step pulse or a trapezoidal pulse in time. By means of dimensional analysis, we identify some dimensionless parameters that can aid the design of structural properties and/or experimental conditions as to ensure that the fluid velocity within the medium remains bounded below a certain given threshold, thereby preventing potential tissue damage. The application to confined compression tests for biological tissues is discussed in detail. Interestingly, the loss of viscoelastic tissue properties has been associated with various disease conditions, such as atherosclerosis, Alzheimer’s disease and glaucoma. Thus, the findings of this work may be relevant to many applications in biology and medicine.

*uniqueness*of such solutions.

We prove that smooth initial data ($H^2 \times H^1$) yields

*regular*solutions that do not depend on the above correlation. Local existence is demonstrated for any source exponent $p\geq 1$ and any monotone damping including feedbacks growing

*exponentially or logarithmically at infinity, or with no damping at all*. The result holds in dimensions 3 and 4, and with some restrictions on $p$ in dimensions $n\geq 5$. Furthermore, if we assert the classical condition that the damping grows as fast as the source, then these regular solutions are global.

*Nonlinear PDEs and Control Theory with Applications*held at the 9th AIMS conference on Dynamical Systems, Differential Equations and Applications in Orlando, July 1--5, 2012.

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