SS20 AIMS 2016 Meeting, Orlando, Florida, USA

Title:  Models for Treatment of Prostate Cancer
Organizer(s):
Name: Affiliation: Country: Email Address:
Fabio MIlner
Arizona State University
USA
milner@asu.edu
Yang Kuang
Arizona State University
USA
kuang@asu.edu
Introduction:
The session will be focused on the description, analysis, and calibration of various models of treatment of prostate cancer in different stages. Most prostate cancers depend on the hormone testosterone to grow. About one-third of prostate cancer patients require hormone therapy when their cancer spreads beyond the prostate or recurs after treatment. Some models will be concerned with intermittent ablation therapy, others with continuous ablation therapy when resistance develops and a new line of treatment is added to suppress intramural testosterone production. Models are calibrated using clinical data from different sources that typically track the Prostate-Specific Antigen (PSA) concentration in patient blood.